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Abstract excerpt: Evidence-based medicine, rooted in randomized controlled trials, offers treatment estimates for the average patient but struggles to guide individualized care. This challenge is amplified in complex conditions like congenital heart disease due to disease variability and limited trial applicability. To address this, medicine-based evidence was proposed to synthesize information for personalized care. A recent article introduced a patient similarity network, CHDmap, which represents a promising technical rendition of the medicine-based evidence concept.