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Abstract
Clinical practice guidelines have become increasingly prominent in clinical medicine over the last 4 decades, and represent one of the most important tools for potentially improving clinical decision-making and, in turn, potentially improving patients’ outcomes.1
Historically, many organizations categorized their guidelines as evidence-based or consensus-based and some organizations, including some of the largest professional organizations devoted to developing clinical practice guidelines for the management of heart disease (the American College of Cardiology and the American Heart Association) and the largest organization devoted to cancer (the American Society of Clinical Oncology), continue to make this distinction.