FREE: Nadir Oxygen Delivery During Pediatric Bypass as a Predictor of Acute Kidney Injury.

Nadir Oxygen Delivery During Pediatric Bypass as a Predictor of Acute Kidney Injury.

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Cardiac surgery–associated acute kidney injury (CS-AKI) is common in infants and is associated with negative outcomes. Nadir indexed oxygen delivery (DO₂i) during cardiopulmonary bypass (CPB) is associated with the occurrence of postoperative CS-AKI, with critical thresholds for DO₂i reported to be 262 to 300 mL/min/m² in adults. However, given that infants have a higher metabolic rate and oxygen demand, the critical DO₂i in infants is not comparable with existing adult standards. This study aimed to explore the critical DO₂i threshold during pediatric CPB.