Start Date: Tuesday, December 15
End Date: Tuesday, December 15
Time: 12:00pm CST
Register Now
Circulating plasma free hemoglobin due to hemolysis poses a significant risk to patients, yet assessing hemolysis in clinical practice remains subject to assay variability and diagnostic gaps.
Join Luc Puis, RRT, ECLS Specialist and founder of the Tiny Perfusion Letter, for a comprehensive educational webinar exploring the underlying pathophysiology of hemolysis, the role and potential toxicity of plasma free hemoglobin (PfHb), and the associated clinical impact.
This session will cover:
- RBC biology: Normal red cell lifespan, clearance mechanisms, and what makes red cells susceptible to lysis
- PfHb toxicity: Nitric oxide scavenging, oxidative stress, inflammation, and microvascular dysfunction
- Clinical consequences: The link between elevated PfHb and outcomes such as acute kidney injury and cardiovascular effects
- Assessing hemolysis: How assessment has evolved, how PfHb compares to LDH, haptoglobin, and bilirubin, and where current methods still fall short
Drawing on more than 20 years of experience in cardiovascular perfusion, Luc will offer perfusionists an evidence-based framework for understanding how precise, reproducible hemolysis monitoring can enhance patient safety and clinical decision-making.
PRESENTER
Luc Puis, RRT, ECLS Specialist
Tiny Perfusion Letter
Luc Puis began his healthcare career as an ICU nurse before completing perfusion training in 1999 at Universitaire Ziekenhuizen Leuven in Belgium. Over an extensive 20-year career in cardiovascular perfusion and ECMO, he developed expertise across the full spectrum of adult cardiac surgery and mechanical circulatory support. Throughout his career, Luc has been deeply committed to advancing the perfusion profession through education, student mentorship, quality improvement, and patient safety, leading to active leadership roles in major international organizations, including BelSECT, AmSECT, the European Board of Cardiovascular Perfusion (EBCP), the International Consortium for Evidence-Based Perfusion (ICEBP), and ELSO.
Relocating to the United States in 2021, Luc expanded his clinical expertise by earning his Registered Respiratory Therapist (RRT) credential and spent two years working as an RRT at University of Iowa Health Care. He now serves as a National Traveling ECLS Specialist with Comprehensive Care Services and as a Perfusion Safety Analyst with Orrum Patient Safety Organization where he continues to champion best practices and quality improvement initiatives across perfusion and extracorporeal support programs.
Among Luc’s proudest professional accomplishments are co-chairing the first European Guidelines for the Conduct of Cardiopulmonary Bypass. He is also a regular speaker at national and international conferences and serves as Associate Editor for the Journal of Extracorporeal Technology (JECT) alongside reviewing for Perfusion and other peer-reviewed journals. Luc is also widely recognized throughout the global perfusion community as the founder and editor of the popular Tiny Perfusion Letter and Tiny ECLS Letter, long-running newsletters dedicated to sharing emerging evidence and practical insights with the perfusion and ECLS communities.
Moderated by Adam Dorzweiler