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Extracorporeal membrane Oxygenation (ECMO) has been successfully delivered in neonates and children for more than 50 years and currently is a well-established form of advanced life support for meconium aspiration syndrome, congenital diaphragmatic hernia (CDH), pediatric acute respiratory distress syndrome (PARDS), postcardiotomy failure, acute myocarditis, cardiomyopathy, and finally for extracorporeal cardiopulmonary resuscitation (ECPR).